Prof. Rudolf Valenta

Valenta
Head of the Division of Immunopathology, Dept. of Pathophysiology and Allergy Research, Medical University of Vienna, Austria.
Professor for Allergology, Medical University of Vienna

Christian Doppler Laboratory for Allergy Research
Division of Immunopathology
Dept. of Pathophysiology and Allergy
Research Center for Pathophysiology, Infectology and Immunology
Medical University of Vienna
Währinger Gürtel 18-20
A-1090 Vienna, Austria
phone: + 431 40400 5108
fax: + 431 40400 5130
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
www.meduniwien.ac.at/allergy-research-christian-doppler
www.allergy-research-program.at

Education

M.D. Degree: University of Vienna
Postdoctoral Training: University of Vienna and University of Manitoba, Winnipeg, Canada.

Research

Research Interests:
• Basic features of antigens and immune recognition of antigens
• Pathomechanisms of IgE-associated allergy
• Development of new forms of diagnosis and therapy for allergy
• Development of new forms of diagnosis and therapy for viral infections

Biography

Rudolf Valenta is Professor for Allergology at the Medical University of Vienna. He has been working in the field of allergy research for more than 20 years. Starting with the molecular and immunological characterization of important allergens he continued to develop recombinant allergen-based diagnostic tests as well as therapeutic allergy vaccines based on recombinant allergens and genetically engineered hypoallergens and advanced them into clinical application. He has been awarded several prestigious national and international awards, among them the START Award of the FWF, the International Pharmacia Award and the Sarstedt Award. Rudolf Valentas work is highly cited, he has published more than 450 original scientific publications, reviews and book chapters, more than 70 patents/patent applications and introduced recombinant allergens into diagnosis and treatment of allergic diseases.

Recent Publications

Biomarkers for Monitoring Clinical Efficacy of Allergen Immunotherapy for Allergic Rhinoconjunctivitis and Allergic Asthma: an EAACI Position Paper.

Shamji MH, Kappen JH, Akdis M, Jensen-Jarolim E, Knol EF, Kleine-Tebbe J, Bohle B, Chaker AM, Till SJ, Valenta R, Poulsen LK, Calderon MA, Demoly P, Pfaar O, Durham LJ, Schmidt-Weber CB.
Allergy. 2017 Feb 2. doi: 10.1111/all.13138. [Epub ahead of print]
PubMed

A B Cell Epitope Peptide Derived from the Major Grass Pollen Allergen Phl p 1 Boosts Allergen-Specific Secondary Antibody Responses without Allergen-Specific T Cell Help.

Narayanan M, Freidl R, Focke-Tejkl M, Baranyi U, Wekerle T, Valenta R, Linhart B.
J Immunol. 2017 Jan 16. pii: 1501741. doi: 10.4049/jimmunol.1501741. [Epub ahead of print]
PubMed

Heat-labile Escherichia coli toxin enhances the induction of allergen-specific IgG antibodies in epicutaneous patch vaccination.

Cabauatan CR, Campana R, Niespodziana K, Reinisch C, Lundberg U, Meinke A, Henning R, Neubauer A, Valenta R.
Allergy. 2017 Jan;72(1):164-168. doi: 10.1111/all.13036.
PubMed

CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells.

Selb R, Eckl-Dorna J, Neunkirchner A, Schmetterer K, Marth K, Gamper J, Jahn-Schmid B, Pickl WF, Valenta R, Niederberger V.
J Allergy Clin Immunol. 2017 Jan;139(1):290-299.e4. doi: 10.1016/j.jaci.2016.03.042.
PubMed

Critical and direct involvement of the CD23 stalk region in IgE binding.

Selb R, Eckl-Dorna J, Twaroch TE, Lupinek C, Teufelberger A, Hofer G, Focke-Tejkl M, Gepp B, Linhart B, Breiteneder H, Ellinger A, Keller W, Roux KH, Valenta R, Niederberger V.
J Allergy Clin Immunol. 2017 Jan;139(1):281-289.e5. doi: 10.1016/j.jaci.2016.04.015.
PubMed